Last Updated:

June 10th, 2025

Taking Acamprosate as Part of the Detox Process

Highlights:
  • Acamprosate is best for individuals who have already detoxed from alcohol
  • Acamprosate reduces cravings and post-withdrawal symptoms
  • Should be taken consistently for the best results
  • Works best alongside therapy and support groups
  • Mild side effects, with diarrhoea being the most common
  • Acamprosate is not addictive and does not cause dependence

What is Acamprosate?

Acamprosate, also known as Campral,  is a medication used to support people in recovery from alcohol addiction. It’s not a cure for addiction, nor does it remove alcohol from your system but it plays an important role in helping to maintain sobriety. It is typically prescribed to people who have already gone through alcohol detox and are committed to staying sober. The goal of Acamprosate is to reduce the urge to drink, making it easier to stay on track during recovery.

This medication is often recommended as part of a structured alcohol addiction programme, alongside therapy, support groups and lifestyle changes. While it won’t prevent withdrawal symptoms or block the effects of alcohol, it helps stabilise brain chemistry in a way that can make long-term sobriety feel more achievable.

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How is Acamprosate taken?

Acamprosate is usually taken in tablet form, with doses spread throughout the day. Most people take two tablets three times a day but this can vary depending on individual circumstances. The medication is best taken at the same times every day to maintain a steady level in the body.

It’s important to note that Campral isn’t intended for short-term use. It’s typically prescribed for several months to help support long-term recovery. For the best results, it should be used as part of a comprehensive alcohol addiction treatment plan, including therapy, counselling and support networks.

Missing a dose doesn’t mean you’ve failed the treatment but consistency is key. If a dose is forgotten, it’s best to take the next one as scheduled rather than doubling up to make up for the missed one. Healthcare professionals will usually provide clear instructions on how to take acamprosate and monitor progress to ensure it’s working effectively.

How does Acamprosate work?

Acamprosate works by helping to rebalance chemicals in the brain that have been affected by long-term alcohol use. When a person drinks heavily for a prolonged period, their brain adapts to the presence of alcohol, altering the way certain neurotransmitters function. Once alcohol is removed, the brain struggles to adjust, which can lead to restlessness, anxiety, irritability and even insomnia. These symptoms make staying sober incredibly difficult.

Campral interacts with these neurotransmitters, particularly glutamate, which plays a key role in excitability and cravings. By stabilising glutamate activity, the medication helps reduce the uncomfortable psychological effects of alcohol withdrawal. This doesn’t mean it eliminates cravings entirely but it does make them more manageable, giving people a stronger foundation to continue their recovery without constant distress.

Unlike some other medications used for alcohol addiction, Campral doesn’t work by blocking the pleasurable effects of alcohol or making people sick if they drink. Instead, it acts more like a support system, helping the brain gradually return to a more balanced state.

Can anyone with alcohol addiction take Acamprosate?

While acamprosate is a well-tolerated medication for many, it’s not suitable for everyone. Certain medical conditions may make it unsafe or less effective, so a healthcare professional will always assess whether it’s the right choice for each individual.

Acamprosate is not recommended for people with severe kidney disease, as their bodies may struggle to process the medication properly. Precautions will need to be made if the medication is chosen for people with these issues. It’s also not typically prescribed to those who are still drinking regularly, as it works best for people who have already stopped drinking and are committed to staying sober.

For those who can take acamprosate, there’s no need to worry about whether it’s the right fit, as healthcare professionals consider all risk factors before prescribing it. If acamprosate isn’t suitable, they will explore alternative options that provide the best support for recovery.

Does Acamprosate stop alcohol cravings completely?

One of the biggest misconceptions about Acamprosate is that it eliminates alcohol cravings entirely. While the medication helps to reduce cravings and lessen the emotional discomfort of staying sober, it does not erase the desire to drink altogether.

There is no single pill that can cure alcohol addiction. Recovery is a complex process that involves more than just taking medication. Campral is most effective when used alongside therapy, support groups and personal lifestyle changes. It provides support, but it doesn’t replace the work needed to maintain long-term sobriety.

Some people find that their cravings become much more manageable with Acamprosate, while others may still experience urges but feel better equipped to resist them. The key is to view the medication as one tool among many rather than a standalone solution.

Is Acamprosate addictive?

 

Acamprosate is not physically addictive, which means there’s no risk of withdrawal symptoms when stopping it. However, some people may develop a psychological reliance on the medication, especially if they feel it’s the only thing helping them stay sober.

This type of psychological dependence isn’t the same as addiction, but it’s understandable. For many, Campral becomes a safety net, like a reassuring presence that helps them resist alcohol. When the time comes to stop taking it, some may worry that their cravings will return in full force, even though this isn’t usually the case.

Healthcare professionals typically advise a gradual approach when discontinuing Campral, ensuring that individuals feel confident in their ability to stay sober without it. Therapy and support networks remain essential throughout this process, helping to reinforce the coping mechanisms needed for long-term recovery.

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What’s next?

If you or someone you care about is struggling with alcohol addiction, you don’t have to face it alone. At Addiction Helper, we provide expert guidance and support to help you find the best treatment options, including rehab programmes that incorporate medications like acamprosate.

Call us now or request a free callback to start your journey to sobriety today.

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Our compassionate team are ready and available to take your call, and guide you towards lasting the lasting addiction recovery you deserve.

Frequently Asked Questions

Does acamprosate cause weight loss?
Acamprosate could lead to weight changes, including weight loss, in some individuals but this is not a common side effect. Any unexpected weight changes should be discussed with a doctor.
What is the success rate of acamprosate?
Acamprosate may improve long-term recovery outcomes when combined with therapy and support. Success rates vary depending on individual commitment, lifestyle changes and adherence to a treatment plan.
Can a GP prescribe acamprosate?
A GP could prescribe acamprosate for alcohol dependence if they determine it is appropriate. However, it is typically part of a broader treatment plan, including counselling and support.
Can you stop acamprosate abruptly?
Acamprosate may be stopped abruptly without causing withdrawal symptoms but it is best to follow medical advice to ensure continued support and effectiveness in maintaining alcohol abstinence.

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